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chromosome: 8; Location: 8 D3; 8 55.0 cM
See Hp in MapViewer
Chromosome eight - NC_000074.5
Go to nucleotideGraphics FASTA GenBank
A high-resolution anatomical atlas with the transcriptome inside the mouse embryo. Diez-Roux G,
Office Professional Plus 2010, et al. PLoS Biol,
Windows 7 Home Basic Key, 2011 Jan eighteen. PMID 21267068.Mechanisms regulating repression of haptoglobin manufacturing by peroxisome proliferator-activated receptor-gamma ligands in adipocytes. Vernochet C, et al. Endocrinology, 2010 Feb. PMID 19952271.Haptoglobin deficiency facilitates the growth of autoimmune inflammation. Galicia G, et al. Eur J Immunol, 2009 Dec. PMID 19795414.The haptoglobin 2-2 genotype is associated with enhanced redox active hemoglobin derived iron from the atherosclerotic plaque. Kalet-Litman S, et al. Atherosclerosis, 2010 Mar. PMID 19775690.Haptoglobin genotype can be a determinant of survival and cardiac remodeling after myocardial infarction in diabetic mice. Asaf R, et al. Cardiovasc Diabetol, 2009 Jun two. PMID 19490627.
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Operate Evidence Code Pubs catalytic exercise IEA hemoglobin binding ISO protein homodimerization exercise ISO serine-type endopeptidase exercise IEA Method Evidence Code Pubs liver advancement ISO negative regulation of hydrogen peroxide catabolic procedure ISO damaging regulation of oxidoreductase exercise ISO constructive regulation of cell death ISO proteolysis IEA response to hydrogen peroxide ISO Component Evidence Code Pubs Golgi apparatus ISO endoplasmic reticulum ISO extracellular area IEA extracellular space ISO haptoglobin-hemoglobin complicated ISO RefSeqs maintained independently of Annotated Genomes
These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome annotation cycle, so their versions might not match the RefSeq versions from the existing genome develop. Establish model mismatches by evaluating the model from the RefSeq during this part on the one particular noted in Genomic regions, transcripts,
Office 2010 Home And Business, and products over.
mRNA and Protein(s)
NM_017370.two → NP_059066.one haptoglobin precursor
Status: VALIDATED
Source sequence(s) AC125162, AK152698,
Genuine Windows 7 Enterprise, M96827 Consensus CDS CCDS40470.one UniProtKB/TrEMBL Q3UBS3 UniProtKB/Swiss-Prot Q61646 Connected Ensembl ENSMUSP, ENSMUST Conserved Domains (one) summary cd00190
Location:103 – 343
Blast Score: 430 Tryp_SPc; Trypsin-like serine protease; A lot of these are synthesized as inactive precursor zymogens which are cleaved for the duration of restricted proteolysis to make their lively kinds. Alignment includes also inactive enzymes which have substitutions with the catalytic... RefSeqs of Annotated Genomes: Construct 37.two
The adhering to sections have reference sequences that belong to a particular genome build. Explain
This part contains genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, these as RefSeqs for chromosomes and scaffolds (contigs) from each reference and alternate assemblies. Model RNAs and proteins can also be reported here.
MGSCv37 C57BL/6J Genomic
NC_000074.5
Variety 112099028..112103072, complement Download GenBank, FASTA, Sequence Viewer (Graphics)
NT_078575.6
Variety 36932382..36936426, complement Download GenBank,
Genuine Office 2010 Key, FASTA, Sequence Viewer (Graphics) Alternate assembly Mm_Celera Genomic
AC_000030.1
Array 113800405..113804474, complement Download GenBank, FASTA, Sequence Viewer (Graphics)
NW_001030904.1
Assortment 37576650..37580719, complement Download GenBank, FASTA, Sequence Viewer (Graphics)