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Old 04-26-2011, 05:05 AM   #1
Intuimaunmaxy
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Drug used to treat impotence, approved by the US Food and Drug Administration (FDA) in March 1998. Viagra works by blocking the enzyme phosphodiesterase, which breaks down cGMP, a relaxant of smooth muscle. The cGMP allows for increased dilation of blood vessels (dilated by nitric oxide) and it is the increase in blood flow that enables two thirds of men suffering from erectile dysfunction to achieve an erection. It must be taken about an hour before intercourse. Side effects include headaches and fainting (due to dilation of blood vessels), and blue-tinted vision. The inhibition of phophodiesterase in the eye may result in damage to the retina as a side effect of taking the drug.
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