amid an unsettling report at the moment of tamiflu resistance within a danish a(h1n1) affected person,
Office 2010 Sale, arrives a review during the new england journal of medicine tracing the swine flu's 90-year evolution.
the present flu strain has genetic roots in an illness that sickened pigs at a swine exhibit in 1918 in cedar rapids, iowa. a near-century of growth seeing as then can comprise this flu's accidental resurrection from an extinct strain.
here is what most likely went down. simultaneously the 1918 flu pandemic was spreading amongst people,
Windows 7 Home Premium Key, pigs were hit with a equivalent respiratory sickness. early experiments confirmed the 1918 swine virus plus a human strain emerged with regards to the very same time.
as outlined by the authors for the new paper,
Office 2007 Activation Key, there was a short-term "extinction" of this strain of virus from humans in 1957. but then it reemerged 20 years later inside of a small 230-person outbreak in 1976 between soldiers in fort dix,
Windows 7 X64, new jersey. that outbreak did not extend beyond the military base.
however the next year h1n1 reemerged in people while in the soviet union, hong kong, and northeastern china. the genetic origin of that 1977 strain turns out not to be the 1976 fort dix strain. instead, it was closely related to a 1950 human strain.
which means that given the genetic similarity with the two strains,
Microsoft Office 2010 Product Key, reemergence was probably due to an accidental release during laboratory studies in the 1950 strain that had been preserved as a "freezer" virus.
ouch. hate it when that happens.
the authors hypothesize that concerns regarding the fort dix outbreak stimulated a flurry of research on h1n1 viruses in 1976, which led to an accidental release and reemergence in the previously extinct virus a 12 months later. the reemerged 1977 h1n1 strain has been circulating in various seasonal influenzas ever since—including today's.
or maybe it wasn't such an accidental a release? conspiracists, restart your engines.