raise a dog, everyone will say this is the wolf, the wolf really raised the discovery, in order to face, had to hug a pet. - This is the China-DPRK relations. (Via: @ Lian Yue)
most people like shit, shit like that is something that I have been called the public like it, exactly like some of the so-called pioneer or not true known by the public. When you are armed to their own day to be just right enough people use the value of the. (Via: @ Left Zuzhou)
microblogging really dead, with the words of Mr. Gu is: this world is utter devotion of the friends,
doudoune moncler pas cher, the enemy must have utter devotion. . . Rivers and lakes Well, where are playing where. . (Via: @ night cool longway)
twenty years ago. Young people like to wear a suit, everyone dressed in their bodies than the suit, two and number; like to wear color * mirror, when the sun did not as transparent, a photo becomes black * a; boys like long hair, like beards; did not have a cell phone, think of the mind many things; their slim than many of today's young people. (Via: @ Pan Shiyi)
『Internet environment in the country, we often encounter a network failure: DNS hijacking, DNS pollution, IP *, server, firewall, IP filtering, server downtime, based on keywords The TCP connection reset, stateless TCP connection reset, SSL certificates filtering, SSL hijacking, HTTP session hijacking and other network problems 』(via: @ rotate8)
help a sister were in a dating site on the children assemble a sign: No Brain easy to cheat, because the big chest. - Now she's concerned about the exponential growth in the number of connections, just to glance at, have been changed 900 5000, and all you stink man! (Via: Lai Po)
reincarnation of a soul of tragedy: In 1949, captured sacrifice; reincarnation, to old, poor family, the case died of famine; reborn, more than ten years old, house-rich, political campaigns, died; reborn, university, died hit by a stray bullet; reborn, drinking Sanlu, the stone and death; reincarnation, primary school, the case of killing died; reborn, 2012. (@ Blues fir)
group of brown is the lowest level Male Ge wall of plants, often collective growth, together with three young amines and cooking oil for a living, most of the snail shell growth. Brown table with three small groups to the official apes could evolve, but how evolutionary need for the relevant decision. Official group of apes and brown crab often decorate the face, Brown said they like this food group, and sometimes they are afraid of truth, the group of brown-away, so they called this group of brown to brown the group and sing the truth.
are so many things happened today, or tragic or violent, leading to the national news editor crazy looking for positive news to balance the layout, a female colleague has just said on the platform Guiqiu harmony draft months fixing. Do not believe to see. (The collar published in April 6) (via: @ Ou Peng AT Mobile Internet)
Brown to step down, step down Kohler, dove mountain station, indicating that Western democracy has reached a dead end, the Chinese model will become the future trend. (Via: @ sinus with Chapter)
teacher said Finance Act: the next remote group of people that you are qualified to laugh at Xifeng in the 500 to work. 】 【Switched campus network
know what is the specialty of Beijing now? Quan Ju De Roast Duck is the fruit,
christian louboutin, or sugar-coated haws, or noodles? NO NO NO, all wrong, in fact, is the specialty of Beijing young women older art ~ ~ ~. (Via: @ we love about joke)
of an ant. One day, the demolition of the bulldozers moved into my nightmare, woke up only after the dwelling of their own rubble. Later, to make a living, I sell corn street level, urban management experience, they smashed cars and sped away after the beating. Since then, I became a tramp living in the bridge opening, the new area overlooking the Expo, the officials of the city life more beautiful. (Via: @ CCT No V)
1, no culture reporter, of course, except the People's Daily. 2, (hospital) lay into, bristling out, this is not normal; lengthwise into, lay out, it is normal. (BY Peking University professor, Peking University, director of forensic Sun Dongdong)
colleagues in the early morning drive to take the company in time, so parked cars when the red light next to the Cayenne, is a beauty, and lower the window Miaole Miao and colleagues are confident that: & ldquo ; certainly mistress! Why such a morning class mistress, grass talks. Chang Hsueh-liang Chiang review to: I have been in existence a fantasy, I think ** is patriotic, I hope the KMT-CPC cooperation Liaojiu China. Said: I am a childish folly, and I do not hate anyone, hate only know ... ... I can not mention the last Jiang Xi'an Incident, Zhang said in his diary: I heard the very sad, not looking down ... ... ( via: @ fog over Lanjiang)
forest is not cruel? Ill hunt, but still good with animals. The universe is not cruel? Desolate no return, but still beautiful with the stars. Society is cruel, life and death, distributors must be well, but it was still good. So I still keep in good cruel, such as dew on spider web storage, underground amber, I know that a stranger may not compassion, but if met, I will cherish the memory, because there to Japan. 【Kang Yong, goodwill message to the cruel society】
21 years ago, children born, has graduated from college soon, irresistible to a generation past, forgotten is the biggest enemy to the memory against forgetting, that is, human civilization premise. (Via: @ Fu Kuo-Chung)
you do not care about politics, but politics certainly care about you, from you is not there, your dead. You are not qualified to come into the world, it is the most fundamental political, without the permission of a paper, your father's sperm can not meet your mother's egg; you hit the vaccine, drink milk, your school, dry work, where you live, you eat you, all depending on the political; you die mercilessly slaughtered by a funeral parlor on the knife, it is shameful that this is the ultimate politics. (Via: @ Cheng in)
child asked Mom: This home D C B babe you? EF does not wear is also a small bare GG
in human history, individuals always been accused of betraying the country. Why can not we reversed, accused of betraying the national individual? Anyway, most countries have used to become a traitor to its citizens. (Via: Ha Jin)
Hunan Province this year, the College Entrance Examination essay question is Not dry it? come ask me why, I have not had time to answer, coming out of a taxi driver, pointing to his nose to scold: This party headquarters is your home? O death, making a note to visitors? To see from the picture is you! Too much bad .....( by Net)
【entrance essay around a large series】 China's ;, the judiciary, (Via: @ Water Galaxy)
A: You look like a sad ###### * repression. B: So I chose to keep knitting a sweater. (Via: dog small remaining 2 World)
trade unions, the strike against the principles of market economy it? No. Market principles is freedom of choice and freedom of contract. In the job market, employers have the freedom of choice, the right end of the transaction, price negotiations, business negotiations can be expanded through the acquisition of power, workers can form unions to increase their forces. If the company can be mergers and acquisitions, but the workers are not free to end it will, the strike, deprived the right to freedom of contract workers. Results will be banned but contrary to market principles to strike. (Via: @ Zhiwu)
day last year, Twitter has been officially screened in China. Also blocked include Hotmail, Bing, Flickr and so on. However, all or part of the other sites later lifted the shield, Twitter has been screened in the state. (Via: @ keso)
old man said: This is life not lived in vain, old, can see sb. Young man said: sb will, sb Council, the scorching sun head TMD really tired. The child said: sb will, long lines, row a while to sleepy. Male family said: sb will, good drunk, I was to spend public funds. (Via: @ Greenwood Hermit)
at KFC, there is an old man would like to point the family barrel, many people attendants could not hear the old man said with a loud voice: . Getting goods underground single waiter very calm, the people have voted to praise around the eyes. (Via: @ Good shirt uprising)
annual college entrance examination again, remembered his years at burning the midnight oil. Members shoes, please do attitude towards the demolition of each question, one way to look for, not A is B, Takeshi Kaneshiro and Lin Chi-ling test is good for you, blew it do not be afraid, mountain wood and Xifeng waiting for you downstairs. (Via @ SARFT ju)
『Q: Who is the best in the history of prostitution * finishes the media? 』『 A: Xinhua radio 』『 Q: Why? 』『 A: Because Xinhua engage in radio communication (draft) 』(via: @ Book Easy)
GG in the discussion group who is the most beautiful woman. There Brigitte Lin, Gong Li has said .... uncle suddenly interrupted by the porter: Do not argue, the most beautiful woman in China called the rationale million machine! One is stunned, uncle explained: You have not heard on TV always said the newspaper, today's leaders came to power for better tomorrow, tomorrow, the leaders came to power but also better tomorrow, the day after tomorrow ...(Monkey King 9527)
Liaoning, happiness is? Happy that I went out to buy food, the family house is not demolished, happiness is what I set up a stall in the street will not be playing, happy every day I do not have to worry about is the child's safety, happiness is what I have grievances, the court can do justice to , happiness is what I rely on their ability to get a good job, and will not be replaced by the children of cadres, officials and the people are happy that is equal and happy that I can live with dignity. (Via: @ Qiangqiang one talk)
』『 Turn
Han guests CNN: Blog writing, such as step steel wire have no means to arrest is dangerous. Sophistry before until I took out a driver's cell phone with GPS, he was my complaints were made. After a middle-aged man and my dad about age, face recognition with a look of shame * money back immediately. To get off, said that, I'm sorry son a few months so there is pressure on the university, I hope he can do physical work like you do not. I can not tell the uncomfortable, out of fifty-plug it back to him, and said that, when you take me for a ride. (Via: @ Choi Sown up)
National Aeronautics and Space Administration (NASA) said they may have in the Saturn's largest moon Titan Titan some unknown creatures have been found on Titan's atmosphere breathe, and the surface of the fuel for food. - This is not a car? Titan is the home of Transformers? . (Via: @ Lian Yue)
】 【knitting [Song Edition] belt she does not regret becoming wide-end is still a silly × knit. Silence alone on the West Wing, as silly ×, knitting a sweater. The sun sets, silly × still knit. Sweater when there is, silly × the sky. Heartbroken at silly mid-×, moon night, knitting a sweater. Zhu Zhang wins light shoes Mountain Horse, Who's Afraid of? Fear silly × knit. The drain, faded away, silly × still in knit. Memories can be misery, like watching a silly × knit. 』『 Turn
newspaper too clean, society will be dirty!
before class, to a large chest of a female college students out on the joint request of the students: After class, big breasts girl answered: downstairs and yells: Big liar! Ya do not say before is how animation director? ! I'm used to doing in the press line, but the bottom line in professional struggles do not fall on top of it, now seems just like a hero guise. I think in the micro-Bo said, not just to humanity fills do not violate common sense, but it caused no small shock to the audience. I know I'm so out of place on a harmonious society. Visible is free to our own, independent of the person sleepy, watch the attitude of my silence was my answer. (Via: @ Cheng in)
Professor Wang said he was most worried about the event is the Chinese people themselves to abolish traditional Chinese medicine, the understanding by the Americans, and reproduction equipment with international patent sold to China ,
louboutin pas cher, just like the effort to understand the spirit of the Americans to sell Chinese . (Via: @ Liang Dong)
been seized since the heaven and earth, had not lost Kunitari! (Via @ yobdc)
Liaoning Volume college entrance essay ! Move fast! Otherwise your peril! ! Go to the airport to send him, before security pulled me into the side of embarrassed to say: . . (Via @ xie107)
Clinton described the Castro: I'm in kindergarten, he is the president; my elementary school, he is the president; I was in high school, he the president; I was in college, he is the president; my work, he was President; I got married, he was President; I became president, he is still President; I step down, he is still president ... & hellip ; (via: woodland path)
just tell my colleagues that: significance of the discovery of the country to see communication and network control in the public discourse on the remedial measures after, this is the problem of government, the Internet, the beginning of the Cultural Revolution, denounced the way the market will be guided in the conduct of the government. Next, companies have chosen to stand in time. (Via: @ New Lang Chen Hui)
the next thing to do watch the U.S. play the disc, with English subtitles will look at the first pass, your plan, will step by step. 【Kang Yong, goodwill message to the cruel society】 (via: @ Kevin Tsai)
Q: There is a problem, why sneeze? A: The sneezing is the most natural nature *, can not control, and from the heart, there is no modification of expression. Comment: Excuse me, I often use paper induced sneeze (in this section by the hilarious orange lemon + Zhang Zhenya + lwnn Relay offers)
Andorid If you take a look and a rub iPhone, resulting in the edge of a Nokia have the program automatically runs, and change to a small doll, the world is full SNS was. (Via: @ and turnips)
Ballmer: Microsoft has lost the mobile position. Microsoft management similar to the film during the Cold War 007: Everything set on an imaginary enemy. But he often chose the wrong opponent: 2001 I work at MSN, AOL when it is the imaginary enemy, AOL fell ill-founded, but missed a big opportunity for the search. Windows Mobile 2004 RIM as the imaginary enemy, the result is lost to the apple. The real enemy is usually in the back, rather than the front. (Via: @ Kuo to illness)
World Literature Network invites you to enjoy: June 2010 Highlights network scripts 『』
a four year old little boy little girl said: will you marry me? Girl: Can you me responsible? Boy: Of course, we are not the two-year-old little boy!
we open to another summit, a summit, and the people from falling into another abyss of an abyss. - Venezuelan President Hugo Chavez said that in 1999, he attended 3 months 6 summit, but then does not help to solve practical problems
2010 Chongqing Entrance essay Unfortunately, this problem has trained me, so I graduated, I found the biggest problem can not find work, so I found a job and find the house has become my life's problems. (Via: @ bazhongwei)
confirmed HootSuite, Xmarks,
abercrombie, Vimeo, Bit.ly, Google GHS closed, the sudden large number of people lifted for overseas instrumental site indicates emotional instability. (Via: @ Moonlight blog)
Shanghai Teachers pay the driver said to me, the Expo is the Chinese people stroke their own to the last stroke, stroke of public funds. (Via: @ Hou Ning)
just discovered a new phenomenon. Amoy men, women dating site is a new word created to subvert the traditional buying pleasure, a woman can abandon the passive real reserved, pushing a shopping cart to enjoy the active selection of men's pleasure. (Via: spicy ginger)
me a man, a handsome guy with his girlfriend last year, ran, did not retain any of how he used, and finally he tearfully said: good you are back! (Via: @ masked eggplant)
Prime Minister in the post is difficult Amy West Amy West. Laid off when the cell is difficult to hear the eight teeth Road. Japan with the text. Across the neighborhood. When can we rely on public opinion and the legal system for the official commutation. Innocence go, easy come. Yikes when someone in the post, no one laid off when the mud horse. (Via: @ Fan Jianchuan)
college entrance examination tips: get the test paper, first rushing to look again, and then muttering aloud: too simple, boring! Give up the left side of the first page, right side started. This way, when others are still doing the first page, you suddenly flip and do the next page. Thus, the examination room where people are nervous breakdown. So you might raise a little admission. (Via: @ and turnips)
2010, Zhejiang college entrance essay You are! Heaven and earth we have the most beautiful girl waiting in the old place go again! The evening will pick who? Farmers left the land became part of the production machines. At this moment, I stood on top of a building Foxconn, looked up at the stars, the stars, or it five stars, but stars do not know my heart. I plunged into the stream and ran to my love of the land, down to earth that ambiguity of her life, I am overflowing with blood. 』『 Turn
Guangdong college entrance essay, east, our friendly socialist neighbors. Their political stability, democratic country in the capitalist pseudo-frequent substitutions, when government leaders, the masses of North Korean leader is widely supported, * shows the superiority of the social system, their technological advancement, self-reliance developed the atomic bomb, he scored a world football cup ... and you are neighbors, we are very proud. (@ Letter sea ray)
crazy seal a great view into the Shanghai World Expo. Legend covered with Chapter 5000 Expo passport can sell dollars, many people visiting the Expo seal became the top priority. It was holding a pile of passports to cover. Kodate few people had also been sealed to the family of speculation into the required queues. Admission to the museum and some do not have to queue long lines sealed. Museum no longer provides a number of stamp services. Australian Museum is simply the chapter fixed, so visitors should looting. (Via: @ Fang)
Food: We are neighbors with the Sanlu, we are neighbors with the waste oil, we are neighbors with the Sudan, we have to add bleach and flour for the neighbors, we dichlorvos ham? For the neighbors, our vegetables with excessive pesticide residues in fruit o, we are neighbors with pig excrement tofu, we smoked drugs with sulfur neighbors chopsticks blisters. And so on. You see, the light used to think so much of foot. 』『 Turn
U.S. labor solidarity with Foxconn can think of: a brush in the center of a country to solidarity, the'd become the enemy of the proletariat. Ironically, this world really is, and we have the irony of the slogan painted on the wall when. (Via: @ Wu Yue San Ren)
upper romance, heart, the results were seriously injured. So afraid of this love hurt, it is retained. This means: the last person that hurt you bad, you get the most complete, and this time the development of the lover, get a very cool of you. I know you are protecting yourself, but if the business, you must down the shop. Off evil never again get the best services, and new customers come, but relatively isolated, how this shop down? 【Kang Yong, love text messages to an unknown lover】
360 conference this afternoon, I re-defined the a Dier out, takes better user a clear picture. Children of the unspoken rules on the table, no company has dared to do evil. If - milk - like the security industry products like the saliva industry scattered, who would dare look inside irrigation melamine ah? There would be no tragedy of the Sanlu. (Via: @ Hong Zhou)
the West is the Best of inventor Thomas Edison, the inventor is the most Niubi Luban; the West is the Best of scientists Albert Einstein, our most牛逼 the scientists Zhang Heng; the West is the Best of the educator John Dewey, the educator in China is the Best of Confucius - that thousands are our Gansha it? (Via: Absalom)
taking advantage of young, talented bad thing to have done it! (Via: @ has Master)
asked me, Hatoyama resigned, why Yukio announced? 2. Even the doors have to rape! 3. So much! Able to have children! buckle down a bit,
moncler sito ufficiale, and then to the teacher. The child said it feels good to managing people. We were trained from childhood and enjoy the informants, some people may grow up in every possible way to correct his own pain, some people a lifetime to the case. What kind of values to the children? Advocating informant teacher, you give an answer right. (Via: @ Wang Qian)
Japan Democratic elections in 4 at noon, Deputy Prime Minister and Finance-phase Naoto Kan (63) as the new representative. Naoto Kan in the afternoon plenary session of the House of Representatives elected office in Japan 94, 61 prime ministers. Hear our colleagues to discuss this news suddenly said one, What he full time? Western text is from left to right, read the time to stop shaking his head, meaning that the text said (A certain university teacher says)
a wealthy Wall Street banks to borrow 5,000 yuan loans, by a period of two weeks, bank loans are secured, wealthy with Rolls-Royce parked in front of as collateral. Bank staff will his Rolls Royce parked in the underground garage, and then lend Regal 5000. After two weeks of the rich to pay back the money, interest of 15 million, the bank staff found that there are millions of rich account, and asked why should borrow money, the rich, said: 15 per week parking lot on Wall Street will never be found . (Via: @ Charles Li)
to write a sentence in the column: the future is worth the wait, even though I went to 64 years old, you are old, we will love each other. - Age of pretext from the Beatles's song, the result was changed to send to (Via: Lian Yue)
a French woman scholar said, in the 20th century the two systems have the same creation of a Nazi and Soviet, can not accept the humble and the evil of human nature * existence. They want a political way is the way of violence, and human nature * to fight. This is totalitarianism. (Via: @ free2000fly)
on all adults in China this year,
franklin and marshall, face to face the Children's Day? When the Children's Day into a child robbed us of the future will be lost. All the adults in China in 2010, Children's Day on this day that all children should apologize to China: I'm sorry, let you suffer the. And a solemn promise: to give you the safest food to eat, the most robust of the house so that you use the most effective security to protect you, the process of acquiring knowledge rather than pleasure pain. (Via: @ Zheng Yuanjie)
cnn: the Government, do you think there is something not worthy of praise? Han: Yes, that is many years ago, they decided to connect to the Internet. But they did not think the consequences will be severe. They think they can control as traditional media, as they did not expect that in addition to the monitor in front of people, as well as keyboard.
Backstage Chun-mei gay crush labor today, and the pain very tough battle, pulled tight lie on the delivery bed, my hand, crying: I have not married, his father's name is a sensitive word, it makes me how to live after ah, 55 ... ... The key is that this child is not in today's life, otherwise his life is sensitive to the word the, 55 ... ... philosophy, life and work together as one, can be used to describe love. Why get rid of the three poisons of life (Six Primary Afflictions), only hard work. Chinese entrepreneurs wished he could hold (Via: @ Feng Xiao)
years ago, the Master of the skin good behavior, because she has a lot of beauty tips. A year, the Master himself aloe planted two basins, with the juice coated face, then his face red, itchy, water linked to the hospital overnight. Then, the doctor sent for picture: This, called aloe vera, and you kind of, um, called the agave, ... ... you did not orally toxic, right? Master said of course not, I'm not stupid ... ... gastric lavage in a few large floor ah? . (Via: @ Ning Caishen)
Why it became the name of the city of Changchun QQ, sensitive words? Customer service staff reporter asked, the answer is: Sensitive word filtering requirements are national unity, our customer service personnel do not have permission Tencent understanding, proposed to re-set the other names used to try. issued a sigh of disappointment. . You are your parents, grandparents are not interested in history because of their ignorance. Because of ignorance, so I do not know what. Wait until you know a little bit of time on the structure of life is exactly when he left,
tell the children how the world, than tell them how the world should be, much more important. Because the latter issue, everyone's answers are dubious. Ancient Chinese teacher is: to teach the answer to the second question, then let them grow their own potential to adapt to the rules (rules of the real world.) Western Humanities Education method: put all the answers in human history, teaching children thinking skills. For parents who choose it. (Via: @ Chen 2006)
Jiangsu entrance theme (Via: @ Xiayuan Feng)
5 18 May, Premier Wen Jiabao met in Beijing with visiting German President Horst Koehler, May 31, Koehler resigned; May 31, visiting Premier in Japan Wen Jiabao Meets with Japanese Prime Minister Hatoyama Yukio; June 2, Hatoyama resigned ... ... there is only one truth: that is, Premier Wen issued tickets! (Via @ mxwu)
famous gay paper 【Shanghai Five Steps】: 2006: I want to hold your hand; 2007: We must cross this bridge; 2008: they ; 2009: The theme of the article Banqiao (Banqiao the Qing Dynasty's largest gay, the object is Yuan Mei); 2010: Materials referred to in Denmark ... (via @ clairming)
micro-Bo is a very convenient driving range, practice your own point of view from someone else's eyes: Why people pay no attention to me? Why do not agree with me? Why not be friends with me? real life, you can hardly ask for them because we all polite, do not say so clearly. but why such a practice is important, because we are often blind to their own advantages and disadvantages, often revel in their own world too. So if want to practice, can be so use microblogging. 【Kang Yong, goodwill message to the cruel society】
This morning I just woke up in bed, radio rang, I heard: I thought, God, ah, Brown want to do, then I think, no, wait a minute, it was me. (British Prime Minister Cameron)
Features * Why socialism always said it? Is not capitalism, color * it? - Odd mobs says
2010 college entrance essay in Hunan Province I'm really speechless. How much? . . I said: When the star. God: Why? I: When the stars make money. Lord: make money doing? I: to the Lord treatment. I: When the doctor. God: Why not become a star? I: Doctors may heal. God: Why treat? I have: money. . . Costa stunned and have never seen this woman ah, but not handsome Columbia consider themselves so directly to the people's sake. Impatient when the girl asked: in the end willing? Nobody wants his aging mother is not! . . . . ! . . . . . . . . . I live off the land to eat. I'm not too country for any costs, I do not have any unlawful records, I even made children to the army. Then I'm alive. If so, I would buy a computer. I've heard a lot of people support me online, I'll have access to support others. . . . ! ! . . . . . . . . . . . . Nice shot! Beautiful! . . . My husband took me out from the library a bottle, and back to study. At this time, year-old daughter cried: Dad, I drink. Impatient husband, said: put up their own! Somewhat taken aback, his daughter, calling to: My husband and I drink. . . . . . . - -! . . Came in front of a solemn voice: public toilets. Hi!
have then a group of children, thought he would liberate, can not wait to go to carnival, and KTV, shopping, dinner, travel, walk proud ... ... but I do not know, they fled to heaven ... .... (Via: @ Li Chengpeng)
Vice President Sun Guanghao Korean Football Association, told the magazine that when the ambition to: North Korean team in the World Cup is the ultimate goal - lifted Hercules Cup, and his confidence is based on this: . (Via: spicy ginger)
while condemning corruption, while in the civil service exam; side of the black heart of the developer in the curse, while you want to buy a house after the skyrocketing housing prices; side in promoting democracy , while dissidents called for the fifty cents; while condemning GCD, while writing an application to join the party; while condemning the state-owned monopoly, while looking for the iron rice bowl ... ... 』『 turn
Hunan volume Premature ejaculation, puppy love, pregnancy, premature, premature aging, premature death, premature ...... to their own experiences prove the harmful effects of early today ... I had an assignment to write this right, an assignment to a ~ ~ (@ letter Sea Light)
have just graduated from child asked, no money to be right at home no money, work hard to find, Beijing, cost of living was so high, how to survive after Na ~ I say you have to explore their advantages, to find a place better than others, and then move in that direction, as long as gold, will be issued misplaced. For a long time that children think: But Beijing nightclubs are better off ... you ... want to go Shanghai to try? . (Via: @ Ning Caishen)
相关的主题文章：
I was won over
如星月一样照亮了我孤寂沉闷的打工生活
Health Department of Hainan Province
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Researchers have discovered how a human egg captures an incoming sperm for fertilization, paving the way to help couples suffering from infertility, according to media reports on Monday.
An international team of researchers found that a sugar chain known as the sialyl-lewis-x sequence (SLeX) makes the outer coat of the egg “sticky,” which has proven to be helpful in binding the egg and the sperm.
As a result, this observation has filled in a huge gap in the understanding of fertility and provides hope for ultimately helping couples who currently cannot conceive.
Scientists and doctors know that a sperm identifies an egg when proteins on the head of the sperm match and bind to a series of specific sugars in the egg’s outer coating. With a successful match of proteins, the outside surfaces of the sperm and egg then bind together before merging, which is then followed by delivery of sperm’s DNA into egg.
To identify this molecules, the researchers used ultra-sensitive mass-spectrometric imaging technology to observe and identify which molecules are most likely to be key in the binding process.
They experimented with a range of synthesised sugars in the laboratory and found that it is SLeX that specifically binds sperm to an egg.
According to the World Health Organisation, infertility affects about 15 percent of reproductive-aged couples around the world and almost one in every seven couples in Britain has problems conceiving a child for various reasons.
SSL hijacking
Hybrid Mode
